Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

Nocodazole

Unique Identifier:LOPAC 01029
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C14H11N3O3S
Molecular Weight:290.234 g/mol
X log p:12.165  (online calculus)
Lipinksi Failures1
TPSA81.03
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:6
Rotatable Bond Count:5
Canonical Smiles:COC(=O)Nc1nc2ccc(cc2n1)C(=O)c1sccc1
Class:Cytoskeleton and ECM
Action:Inhibitor
Selectivity:beta-tubulin

Found: 11 active | as graph: single | with analogs 1 2 3 4 5 6 7 8 9 10  Next >> 
Species: 4932
Condition: BY4741
Replicates: 8
Raw OD Value: r im 0.4014±0.146024
Normalized OD Score: sc h 0.5060±0.215026
Z-Score: -21.6215±7.69296
p-Value: 0
Z-Factor: -0.664927
Fitness Defect: INF
Bioactivity Statement: Outlier
Experimental Conditions
Library:Lopac
Plate Number and Position:10|B4
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.70 Celcius
Date:2005-04-07 YYYY-MM-DD
Plate CH Control (+):0.047456250000000026±0.00556
Plate DMSO Control (-):0.76401875±0.03843
Plate Z-Factor:0.8776
png
ps
pdf

DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 0

active | Cluster 3124 | Additional Members: 12 | Rows returned: 4
Prest1273 0.491803278688525
LAT002F08 0
SPE01501110 0
Prest310 0

Service provided by the Mike Tyers Laboratory