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Compound InformationSONAR Target prediction
Name:

S-(-)-Lisuride

Unique Identifier:LOPAC 01021
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C20H26N4O
Molecular Weight:314.256 g/mol
X log p:9.775  (online calculus)
Lipinksi Failures1
TPSA23.55
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:5
Rotatable Bond Count:5
Canonical Smiles:CCN(CC)C(=O)NC1CN(C)C2Cc3cnc4cccc(C2=C1)c34
Class:Dopamine
Action:Agonist
Selectivity:DRD2

Found: 24 nonactive as graph: single | with analogs [1] << Back 21 22 23 24 Next >> [24]
Species: 4932
Condition: tep1-2nd
Replicates: 2
Raw OD Value: r im 0.7657±0.0121622
Normalized OD Score: sc h 0.9912±0.00473913
Z-Score: -0.3318±0.175963
p-Value: 0.741958
Z-Factor: -31.0406
Fitness Defect: 0.2985
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:10|G2
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:0.00 Celcius
Date:2005-07-07 YYYY-MM-DD
Plate CH Control (+):0.044125±0.00207
Plate DMSO Control (-):0.719775±0.02778
Plate Z-Factor:0.8687
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 1
LOPAC 00289 0.9531

active | Cluster 4543 | Additional Members: 12 | Rows returned: 1
Prest308 0.343283582089552

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