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Compound InformationSONAR Target prediction
Name:

S-(-)-Lisuride

Unique Identifier:LOPAC 01021
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C20H26N4O
Molecular Weight:314.256 g/mol
X log p:9.775  (online calculus)
Lipinksi Failures1
TPSA23.55
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:5
Rotatable Bond Count:5
Canonical Smiles:CCN(CC)C(=O)NC1CN(C)C2Cc3cnc4cccc(C2=C1)c34
Class:Dopamine
Action:Agonist
Selectivity:DRD2

Found: 24 nonactive as graph: single | with analogs [1] << Back 11 12 13 14 15 16 17 18 19 20  Next >> [24]
Species: 4932
Condition: NOP16
Replicates: 2
Raw OD Value: r im 0.7450±0.00777817
Normalized OD Score: sc h 1.0043±0.00707876
Z-Score: 0.2220±0.354576
p-Value: 0.806748
Z-Factor: -10.065
Fitness Defect: 0.2147
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:10|G2
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:0.00 Celcius
Date:2005-04-22 YYYY-MM-DD
Plate CH Control (+):0.04525±0.00121
Plate DMSO Control (-):0.703225±0.02745
Plate Z-Factor:0.8709
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 1
LOPAC 00289 0.9531

active | Cluster 4543 | Additional Members: 12 | Rows returned: 1
Prest308 0.343283582089552

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