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Compound InformationSONAR Target prediction
Name:

p-Fluoro-L-phenylalanine

Unique Identifier:LOPAC 00912
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C9FH10NO2
Molecular Weight:173.1 g/mol
X log p:7.173  (online calculus)
Lipinksi Failures1
TPSA17.07
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:3
Rotatable Bond Count:3
Canonical Smiles:NC(Cc1ccc(F)cc1)C(O)=O
Class:Neurotransmission
Action:Substrate
Selectivity:Tyrosine Hydroxylase

Found: 24 nonactive as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [24]
Species: 4932
Condition: GAS1
Replicates: 2
Raw OD Value: r im 0.6685±0.0181019
Normalized OD Score: sc h 0.9761±0.0142125
Z-Score: -1.1476±0.682354
p-Value: 0.304536
Z-Factor: -2.88204
Fitness Defect: 1.189
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:7|G6
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.30 Celcius
Date:2005-11-17 YYYY-MM-DD
Plate CH Control (+):0.039575±0.00156
Plate DMSO Control (-):0.6731499999999999±0.01603
Plate Z-Factor:0.9256
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DBLink | Rows returned: 71 2 Next >> 
4654 2-amino-3-(4-fluorophenyl)propanoic acid
450592 2-amino-3-(4-fluorophenyl)propanoic acid
450593 (2S)-2-amino-3-(4-fluorophenyl)-2-methyl-propanoic acid
716312 (2S)-2-amino-3-(4-fluorophenyl)propanoic acid
716314 (2R)-2-amino-3-(4-fluorophenyl)propanoic acid
6926425 (2S)-2-azaniumyl-3-(4-fluorophenyl)propanoate

internal high similarity DBLink | Rows returned: 1
SPE01502114 1.0000

nonactive | Cluster 1385 | Additional Members: 11 | Rows returned: 6
LOPAC 01033 0.444444444444444
SPE01500382 0.444444444444444
SPE01502162 0.384615384615385
LOPAC 00493 0.384615384615385
LAT003F10 0
SPE01502114 0

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