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Compound InformationSONAR Target prediction
Name:

p-Fluoro-L-phenylalanine

Unique Identifier:LOPAC 00912
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C9FH10NO2
Molecular Weight:173.1 g/mol
X log p:7.173  (online calculus)
Lipinksi Failures1
TPSA17.07
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:3
Rotatable Bond Count:3
Canonical Smiles:NC(Cc1ccc(F)cc1)C(O)=O
Class:Neurotransmission
Action:Substrate
Selectivity:Tyrosine Hydroxylase

Found: 24 nonactive as graph: single | with analogs [1] << Back 21 22 23 24 Next >> [24]
Species: 4932
Condition: tep1-2nd
Replicates: 2
Raw OD Value: r im 0.7969±0.0311834
Normalized OD Score: sc h 0.9791±0.0362145
Z-Score: -0.7991±1.38324
p-Value: 0.466748
Z-Factor: -22.2682
Fitness Defect: 0.762
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:7|G6
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:0.00 Celcius
Date:2005-07-07 YYYY-MM-DD
Plate CH Control (+):0.043375±0.00244
Plate DMSO Control (-):0.7643±0.03481
Plate Z-Factor:0.7850
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DBLink | Rows returned: 71 2 Next >> 
4654 2-amino-3-(4-fluorophenyl)propanoic acid
450592 2-amino-3-(4-fluorophenyl)propanoic acid
450593 (2S)-2-amino-3-(4-fluorophenyl)-2-methyl-propanoic acid
716312 (2S)-2-amino-3-(4-fluorophenyl)propanoic acid
716314 (2R)-2-amino-3-(4-fluorophenyl)propanoic acid
6926425 (2S)-2-azaniumyl-3-(4-fluorophenyl)propanoate

internal high similarity DBLink | Rows returned: 1
SPE01502114 1.0000

active | Cluster 1385 | Additional Members: 11 | Rows returned: 0
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