Compound Information | SONAR Target prediction | Name: | 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid | Unique Identifier: | LOPAC 00855 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | C22H40O2 | Molecular Weight: | 296.234 g/mol | X log p: | 7.358 (online calculus) | Lipinksi Failures | 2 | TPSA | 17.07 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 2 | Rotatable Bond Count: | 16 | Canonical Smiles: | CCCCCCCCCCCC=CC(C)(C)C=CCCCC(O)=O | Class: | Lipid | Action: | Inhibitor | Selectivity: | PLA2 / Lipoxygenase |
Species: |
4932 |
Condition: |
MT2481-pdr1pdr3 |
Replicates: |
2 |
Raw OD Value: r im |
0.6414±0.0106773 |
Normalized OD Score: sc h |
0.9777±0.00386705 |
Z-Score: |
-1.2506±0.132853 |
p-Value: |
0.213092 |
Z-Factor: |
-2.58589 |
Fitness Defect: |
1.546 |
Bioactivity Statement: |
Nonactive |
Experimental Conditions | | Library: | Lopac | Plate Number and Position: | 6|G3 | Drug Concentration: | 50.00 nM | OD Absorbance: | 600 nm | Robot Temperature: | 27.70 Celcius | Date: | 2005-04-08 YYYY-MM-DD | Plate CH Control (+): | 0.04605±0.00127 | Plate DMSO Control (-): | 0.647725±0.01234 | Plate Z-Factor: | 0.9304 |
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5312333 |
(5E,8E,11E)-10,10-dimethylicosa-5,8,11-trienoic acid |
5312474 |
(5E,8E)-octadeca-5,8-dienoic acid |
5312492 |
(5E,8E,11E)-octadeca-5,8,11-trienoic acid |
5312531 |
(5E,8E,11E)-icosa-5,8,11-trienoic acid |
5353602 |
(5E,8E)-icosa-5,8-dienoic acid |
6443300 |
(5E,8E)-octadeca-5,8-dienoic acid |
internal high similarity DBLink | Rows returned: 1 | |
active | Cluster 13466 | Additional Members: 2 | Rows returned: 0 | |
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