| Compound Information | SONAR Target prediction | | Name: | 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid | | Unique Identifier: | LOPAC 00855 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | C22H40O2 | | Molecular Weight: | 296.234 g/mol | | X log p: | 7.358 (online calculus) | | Lipinksi Failures | 2 | | TPSA | 17.07 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 2 | | Rotatable Bond Count: | 16 | | Canonical Smiles: | CCCCCCCCCCCC=CC(C)(C)C=CCCCC(O)=O | | Class: | Lipid | | Action: | Inhibitor | | Selectivity: | PLA2 / Lipoxygenase |
| Species: |
4932 |
| Condition: |
LGE1 |
| Replicates: |
2 |
| Raw OD Value: r im |
0.4741±0.0284257 |
| Normalized OD Score: sc h |
1.0774±0.0686775 |
| Z-Score: |
2.6228±2.27957 |
| p-Value: |
0.156049 |
| Z-Factor: |
-3.01955 |
| Fitness Defect: |
1.8576 |
| Bioactivity Statement: |
Nonactive |
| Experimental Conditions | | | Library: | Lopac | | Plate Number and Position: | 6|G3 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 600 nm | | Robot Temperature: | 25.70 Celcius | | Date: | 2005-11-29 YYYY-MM-DD | | Plate CH Control (+): | 0.038349999999999995±0.00060 | | Plate DMSO Control (-): | 0.44342500000000007±0.01269 | | Plate Z-Factor: | 0.9052 |
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| 5312333 |
(5E,8E,11E)-10,10-dimethylicosa-5,8,11-trienoic acid |
| 5312474 |
(5E,8E)-octadeca-5,8-dienoic acid |
| 5312492 |
(5E,8E,11E)-octadeca-5,8,11-trienoic acid |
| 5312531 |
(5E,8E,11E)-icosa-5,8,11-trienoic acid |
| 5353602 |
(5E,8E)-icosa-5,8-dienoic acid |
| 6443300 |
(5E,8E)-octadeca-5,8-dienoic acid |
| internal high similarity DBLink | Rows returned: 1 | |
| active | Cluster 13466 | Additional Members: 2 | Rows returned: 0 | |
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