| Compound Information | SONAR Target prediction | | Name: | Droperidol | | Unique Identifier: | LOPAC 00821 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | C22FH22N3O2 | | Molecular Weight: | 357.253 g/mol | | X log p: | 21.208 (online calculus) | | Lipinksi Failures | 1 | | TPSA | 40.62 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 5 | | Rotatable Bond Count: | 6 | | Canonical Smiles: | Fc1ccc(cc1)C(=O)CCCN1CCC(C=C1)N1C(=O)Nc2ccccc12 | | Class: | Dopamine | | Action: | Antagonist | | Selectivity: | D1/D2 |
| Species: |
4932 |
| Condition: |
SAP30 |
| Replicates: |
2 |
| Raw OD Value: r im |
0.8217±0.0154856 |
| Normalized OD Score: sc h |
1.0005±0.00486162 |
| Z-Score: |
0.0534±0.422149 |
| p-Value: |
0.765642 |
| Z-Factor: |
-41.521 |
| Fitness Defect: |
0.267 |
| Bioactivity Statement: |
Nonactive |
| Experimental Conditions | | | Library: | Lopac | | Plate Number and Position: | 5|C7 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 600 nm | | Robot Temperature: | 26.10 Celcius | | Date: | 2005-11-18 YYYY-MM-DD | | Plate CH Control (+): | 0.03985±0.00423 | | Plate DMSO Control (-): | 0.800225±0.01150 | | Plate Z-Factor: | 0.9575 |
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| DBLink | Rows returned: 1 | |
| 6603813 |
1-[(4S)-1-[4-(4-fluorophenyl)-4-oxo-butyl]-3,4-dihydro-2H-pyridin-4-yl]-3H-benzoimidazol-2-one |
| internal high similarity DBLink | Rows returned: 0 | |
| active | Cluster 5771 | Additional Members: 4 | Rows returned: 0 | |
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