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Compound InformationSONAR Target prediction
Name:

(S)-(+)-Camptothecin

Unique Identifier:LOPAC 00814
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C20H16N2O4
Molecular Weight:332.225 g/mol
X log p:11.182  (online calculus)
Lipinksi Failures1
TPSA58.97
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:6
Rotatable Bond Count:1
Canonical Smiles:CCC1(O)C(=O)OCC2C(=O)N3Cc4cc5ccccc5nc4C3=CC=21
Class:Apoptosis
Action:Inhibitor
Selectivity:TopoI

Found: 11 active | as graph: single | with analogs << Back 1 2 3 4 5 6 7 8 9 10  Next >> 
Species: 4932
Condition: MT2481-pdr1pdr3
Replicates: 2
Raw OD Value: r im 0.5501±0.0529623
Normalized OD Score: sc h 0.8807±0.0188795
Z-Score: -6.6856±0.609372
p-Value: 0.000000000199736
Z-Factor: -0.338474
Fitness Defect: 22.334
Bioactivity Statement: Active
Experimental Conditions
Library:Lopac
Plate Number and Position:5|C2
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.70 Celcius
Date:2005-04-08 YYYY-MM-DD
Plate CH Control (+):0.04585±0.00120
Plate DMSO Control (-):0.631675±0.02376
Plate Z-Factor:0.8151
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DBLink | Rows returned: 5
2538
24360
32939
153546
184196

internal high similarity DBLink | Rows returned: 2
SPE01504123 0.9800
SPE01502232 1.0000

nonactive | Cluster 1530 | Additional Members: 9 | Rows returned: 6
SPE01505821 0.535714285714286
SPE01504123 0.178082191780822
LAT002A02 0
SPE01502232 0
Prest102 0
LAT003C09 0

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