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Compound InformationSONAR Target prediction
Name:

(S)-(+)-Camptothecin

Unique Identifier:LOPAC 00814
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C20H16N2O4
Molecular Weight:332.225 g/mol
X log p:11.182  (online calculus)
Lipinksi Failures1
TPSA58.97
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:6
Rotatable Bond Count:1
Canonical Smiles:CCC1(O)C(=O)OCC2C(=O)N3Cc4cc5ccccc5nc4C3=CC=21
Class:Apoptosis
Action:Inhibitor
Selectivity:TopoI

Found: 11 active | as graph: single | with analogs << Back 11
Species: 4932
Condition: WHI5
Replicates: 2
Raw OD Value: r im 0.5125±0.0245366
Normalized OD Score: sc h 0.8674±0.0282373
Z-Score: -4.0610±1.33595
p-Value: 0.000915684
Z-Factor: -6.79147
Fitness Defect: 6.9958
Bioactivity Statement: Active
Experimental Conditions
Library:Lopac
Plate Number and Position:5|C2
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:0.00 Celcius
Date:2005-04-20 YYYY-MM-DD
Plate CH Control (+):0.044675±0.00123
Plate DMSO Control (-):0.668975±0.08457
Plate Z-Factor:0.5315
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DBLink | Rows returned: 5
2538
24360
32939
153546
184196

internal high similarity DBLink | Rows returned: 2
SPE01504123 0.9800
SPE01502232 1.0000

active | Cluster 1530 | Additional Members: 9 | Rows returned: 5
SPE01504123 0.178082191780822
LAT002A02 0
SPE01502232 0
Prest102 0
LAT003C09 0

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