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Compound InformationSONAR Target prediction
Name:

(S)-(+)-Camptothecin

Unique Identifier:LOPAC 00814
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C20H16N2O4
Molecular Weight:332.225 g/mol
X log p:11.182  (online calculus)
Lipinksi Failures1
TPSA58.97
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:6
Rotatable Bond Count:1
Canonical Smiles:CCC1(O)C(=O)OCC2C(=O)N3Cc4cc5ccccc5nc4C3=CC=21
Class:Apoptosis
Action:Inhibitor
Selectivity:TopoI

Found: 13 nonactive | as graph: single | with analogs << Back 1 2 3 4 5 6 7 8 9 10  Next >> 
Species: 4932
Condition: MRC1
Replicates: 2
Raw OD Value: r im 0.8069±0.0161927
Normalized OD Score: sc h 0.9774±0.00588791
Z-Score: -1.6701±0.58635
p-Value: 0.123209
Z-Factor: -1.86528
Fitness Defect: 2.0939
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:5|C2
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:24.90 Celcius
Date:2005-12-06 YYYY-MM-DD
Plate CH Control (+):0.3314±0.21684
Plate DMSO Control (-):0.813625±0.01988
Plate Z-Factor:0.4359
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DBLink | Rows returned: 5
2538
24360
32939
153546
184196

internal high similarity DBLink | Rows returned: 2
SPE01504123 0.9800
SPE01502232 1.0000

active | Cluster 1530 | Additional Members: 9 | Rows returned: 5
SPE01504123 0.178082191780822
LAT002A02 0
SPE01502232 0
Prest102 0
LAT003C09 0

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