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Compound InformationSONAR Target prediction
Name:

Corticosterone

Unique Identifier:LOPAC 00759
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C21H30O4
Molecular Weight:319.246 g/mol
X log p:0.527  (online calculus)
Lipinksi Failures0
TPSA34.14
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:4
Rotatable Bond Count:2
Canonical Smiles:CC12CC(O)C3C(CCC4=CC(=O)CCC34C)C1CCC2C(=O)CO
Class:Hormone
Selectivity:Glucocorticoid

Found: 24 nonactive as graph: single | with analogs [1] << Back 11 12 13 14 15 16 17 18 19 20  Next >> [24]
Species: 4932
Condition: LGE1
Replicates: 2
Raw OD Value: r im 0.4534±0.0172534
Normalized OD Score: sc h 0.9958±0.00227805
Z-Score: -0.1437±0.0823614
p-Value: 0.885914
Z-Factor: -90.5854
Fitness Defect: 0.1211
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:3|F11
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.30 Celcius
Date:2005-11-29 YYYY-MM-DD
Plate CH Control (+):0.038475±0.00058
Plate DMSO Control (-):0.47057499999999997±0.00752
Plate Z-Factor:0.9284
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DBLink | Rows returned: 11<< Back 1 2
4122713 8-hydroxy-17-(2-hydroxyacetyl)-13-methyl-1,2,6,7,9,10,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanth
ren-3-one
5316088 (4aR,5S,6aR,7S)-5-hydroxy-7-(2-hydroxyacetyl)-4a,6a-dimethyl-4,4b,5,6,7,8,9,10,10a,10b,11,12-dodecahydro
-3H-chrysen-2-one
6540812 (8S,9R,10R,11S,13S,14S,17R)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17
-dodecahydrocyclopenta[a]phenanthren-3-one
6603769 (8S,9S,10S,11R,13S,14R,17R)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17
-dodecahydrocyclopenta[a]phenanthren-3-one
6918887 (8R,9S,10S,11R,13R,14R,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17
-dodecahydrocyclopenta[a]phenanthren-3-one

internal high similarity DBLink | Rows returned: 6
LOPAC 00951 0.9184
SPE01701060 0.9200
NRB 03831 0.9592
SPE01500380 0.9600
LOPAC 00948 0.9608
SPE00300024 0.9615

active | Cluster 10196 | Additional Members: 12 | Rows returned: 0

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