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Compound InformationSONAR Target prediction
Name:

Chlorprothixene hydrochloride

Unique Identifier:LOPAC 00755
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C18Cl2H19NS
Molecular Weight:333.171 g/mol
X log p:17.85  (online calculus)
Lipinksi Failures1
TPSA28.54
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:1
Rotatable Bond Count:3
Canonical Smiles:Cl.CN(C)CCC=C1c2ccccc2Sc2cc(Cl)ccc21
Class:Dopamine
Action:Antagonist
Selectivity:DRD2

Found: 17 nonactive | as graph: single | with analogs << Back 11 12 13 14 15 16 17 Next >> 
Species: 4932
Condition: tep1-2nd
Replicates: 2
Raw OD Value: r im 0.6606±0.0956715
Normalized OD Score: sc h 0.9781±0.00316092
Z-Score: -0.8334±0.129572
p-Value: 0.406612
Z-Factor: -3.97515
Fitness Defect: 0.8999
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:3|A11
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:0.00 Celcius
Date:2005-07-07 YYYY-MM-DD
Plate CH Control (+):0.043225±0.00193
Plate DMSO Control (-):0.632425±0.01870
Plate Z-Factor:0.9205
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DBLink | Rows returned: 1
6603768 (3E)-3-(3-chlorothioxanthen-9-ylidene)-N,N-dimethyl-propan-1-amine

internal high similarity DBLink | Rows returned: 0

active | Cluster 11809 | Additional Members: 3 | Rows returned: 1
SPE01503203 0

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