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Compound Information
SONAR Target prediction
Name:
Androsterone
Unique Identifier:
LOPAC 00697
MolClass:
Checkout models in
ver1.5
and
ver1.0
Molecular Formula:
C19H30O2
Molecular Weight:
263.226 g/mol
X log p:
-0.358
(online calculus)
Lipinksi Failures
0
TPSA
17.07
Hydrogen Bond Donor Count:
0
Hydrogen Bond Acceptors Count:
2
Rotatable Bond Count:
0
Canonical Smiles:
CC12CCC(O)CC1CCC1C2CCC2(C)C1CCC2=O
Class:
Hormone
Selectivity:
Androgen
Generic_name:
AETIOCHOLANOLONE
Chemical_iupac_name:
AETIOCHOLANOLONE
Drug_type:
Experimental
Drugbank_id:
EXPT00443
Drug_category:
Alcohol Sulfotransferase inhibitor
Organisms_affected:
-1
Found: 2
active
| as graph:
single
|
with analogs
1
2
Next >>
Species:
4932
Condition:
DEP1
Replicates:
2
Raw OD Value:
r
im
0.5809±0.0166877
Normalized OD Score:
sc
h
0.8948±0.0304884
Z-Score:
-4.3491±1.44685
p-Value:
0.000440462
Z-Factor:
-0.870248
Fitness Defect:
7.7277
Bioactivity Statement:
Active
Experimental Conditions
Library:
Lopac
Plate Number and Position:
2|G5
Drug Concentration:
50.00 nM
OD Absorbance:
600 nm
Robot Temperature:
26.90 Celcius
Date:
2005-11-16 YYYY-MM-DD
Plate CH Control (+):
0.03855±0.00129
Plate DMSO Control (-):
0.64055±0.02116
Plate Z-Factor:
0.8634
png
ps
pdf
DBLink | Rows returned: 323
[1]
<< Back
51
52
53
54
8015697
(5R,8R,9S,10S,13S,14R,17R)-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyc
lopenta[a]phenanthren-3-one
11000589
1-hydroxyoctadecan-9-one
11978239
n/a
15940313
n/a
15940314
n/a
internal high similarity DBLink | Rows returned: 5
LOPAC 01140
0.9474
LOPAC 01166
1.0000
NRB 03688
1.0000
SPE00100303
1.0000
SPE00310009
1.0000
nonactive
| Cluster 11774 | Additional Members: 14 | Rows returned: 8
1
2
Next >>
SPE00107108
0.377049180327869
SPE00107113
0.353846153846154
SPE01503675
0.34375
SPE00100586
0.275862068965517
SPE00310009
0
Prest1062
0
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Mike Tyers Laboratory