| Compound Information | SONAR Target prediction | | Name: | Androsterone | | Unique Identifier: | LOPAC 00697 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | C19H30O2 | | Molecular Weight: | 263.226 g/mol | | X log p: | -0.358 (online calculus) | | Lipinksi Failures | 0 | | TPSA | 17.07 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 2 | | Rotatable Bond Count: | 0 | | Canonical Smiles: | CC12CCC(O)CC1CCC1C2CCC2(C)C1CCC2=O | | Class: | Hormone | | Selectivity: | Androgen | | Generic_name: | AETIOCHOLANOLONE | | Chemical_iupac_name: | AETIOCHOLANOLONE | | Drug_type: | Experimental | | Drugbank_id: | EXPT00443 | | Drug_category: | Alcohol Sulfotransferase inhibitor | | Organisms_affected: | -1 |
| Species: |
4932 |
| Condition: |
BY4741 |
| Replicates: |
8 |
| Raw OD Value: r im |
0.8188±0.0889757 |
| Normalized OD Score: sc h |
0.9873±0.0444372 |
| Z-Score: |
-0.4847±1.10785 |
| p-Value: |
0.481946 |
| Z-Factor: |
-18.6776 |
| Fitness Defect: |
0.7299 |
| Bioactivity Statement: |
Nonactive |
| Experimental Conditions | | | Library: | Lopac | | Plate Number and Position: | 2|G5 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 600 nm | | Robot Temperature: | 27.60 Celcius | | Date: | 2005-04-07 YYYY-MM-DD | | Plate CH Control (+): | 0.046749999999999986±0.00334 | | Plate DMSO Control (-): | 0.7916312500000005±0.04022 | | Plate Z-Factor: | 0.8778 |
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ps
pdf |
| 7052737 |
(5R,8S,9S,10S,13R,14R)-14-hydroxy-10,13-dimethyl-2,4,5,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[
a]phenanthren-3-one |
| 7052895 |
1-[(3R,5S,8S,9R,10R,13R,14R,17R)-17-hydroxy-5,10,13-trimethyl-1,2,3,4,6,7,8,9,11,12,14,15,16,17-tetradec
ahydrocyclopenta[a]phenanthren-3-yl]ethanone |
| 7052896 |
1-[(3S,5S,8S,9R,10R,13R,14R,17R)-17-hydroxy-5,10,13-trimethyl-1,2,3,4,6,7,8,9,11,12,14,15,16,17-tetradec
ahydrocyclopenta[a]phenanthren-3-yl]ethanone |
| 7052897 |
1-[(3R,5S,8S,9R,10S,13R,14R,17R)-17-hydroxy-5,10,13-trimethyl-1,2,3,4,6,7,8,9,11,12,14,15,16,17-tetradec
ahydrocyclopenta[a]phenanthren-3-yl]ethanone |
| 7052898 |
1-[(3S,5S,8S,9R,10S,13R,14R,17R)-17-hydroxy-5,10,13-trimethyl-1,2,3,4,6,7,8,9,11,12,14,15,16,17-tetradec
ahydrocyclopenta[a]phenanthren-3-yl]ethanone |
| 7052899 |
(5R,7R,8S,9S,10R,13R,14S,17S)-17-hydroxy-7,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahy
drocyclopenta[a]phenanthren-3-one |
| internal high similarity DBLink | Rows returned: 5 | |
| active | Cluster 11774 | Additional Members: 14 | Rows returned: 5 | |
|
