| Compound Information | SONAR Target prediction | | Name: | Androsterone | | Unique Identifier: | LOPAC 00697 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | C19H30O2 | | Molecular Weight: | 263.226 g/mol | | X log p: | -0.358 (online calculus) | | Lipinksi Failures | 0 | | TPSA | 17.07 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 2 | | Rotatable Bond Count: | 0 | | Canonical Smiles: | CC12CCC(O)CC1CCC1C2CCC2(C)C1CCC2=O | | Class: | Hormone | | Selectivity: | Androgen | | Generic_name: | AETIOCHOLANOLONE | | Chemical_iupac_name: | AETIOCHOLANOLONE | | Drug_type: | Experimental | | Drugbank_id: | EXPT00443 | | Drug_category: | Alcohol Sulfotransferase inhibitor | | Organisms_affected: | -1 |
| Species: |
4932 |
| Condition: |
SMI1 |
| Replicates: |
2 |
| Raw OD Value: r im |
0.4161±0.0556493 |
| Normalized OD Score: sc h |
0.6360±0.0939235 |
| Z-Score: |
-10.0747±3.36632 |
| p-Value: |
0.00000000000000710878 |
| Z-Factor: |
-0.382943 |
| Fitness Defect: |
32.5774 |
| Bioactivity Statement: |
Active |
| Experimental Conditions | | | Library: | Lopac | | Plate Number and Position: | 2|G5 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 600 nm | | Robot Temperature: | 27.10 Celcius | | Date: | 2005-11-15 YYYY-MM-DD | | Plate CH Control (+): | 0.038875±0.00156 | | Plate DMSO Control (-): | 0.665675±0.04194 | | Plate Z-Factor: | 0.8595 |
|  png
ps
pdf |
| 7002669 |
(5S,8S,9R,10R,13S,14R,17S)-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyc
lopenta[a]phenanthren-3-one |
| 7003235 |
(5S,8R,9S,10S,13S,14R,17R)-17-hydroxy-10,13-dimethyl-17-propyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-
1H-cyclopenta[a]phenanthren-3-one |
| 7032609 |
(2R)-2-(11-hydroxyundecyl)cyclopentan-1-one |
| 7032610 |
(2S)-2-(11-hydroxyundecyl)cyclopentan-1-one |
| 7048583 |
(5R,8R,9R,10S,13S,14R,17R)-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyc
lopenta[a]phenanthren-3-one |
| 7052376 |
1-[(3R,5R,8R,9R,10R,13R,14S,17R)-17-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahy
dro-1H-cyclopenta[a]phenanthren-3-yl]ethanone |
| internal high similarity DBLink | Rows returned: 5 | |
| active | Cluster 11774 | Additional Members: 14 | Rows returned: 5 | |
|
