Compound Information | SONAR Target prediction | Name: | Androsterone | Unique Identifier: | LOPAC 00697 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | C19H30O2 | Molecular Weight: | 263.226 g/mol | X log p: | -0.358 (online calculus) | Lipinksi Failures | 0 | TPSA | 17.07 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 2 | Rotatable Bond Count: | 0 | Canonical Smiles: | CC12CCC(O)CC1CCC1C2CCC2(C)C1CCC2=O | Class: | Hormone | Selectivity: | Androgen | Generic_name: | AETIOCHOLANOLONE | Chemical_iupac_name: | AETIOCHOLANOLONE | Drug_type: | Experimental | Drugbank_id: | EXPT00443 | Drug_category: | Alcohol Sulfotransferase inhibitor | Organisms_affected: | -1 |
Species: |
4932 |
Condition: |
DEP1 |
Replicates: |
2 |
Raw OD Value: r im |
0.5809±0.0166877 |
Normalized OD Score: sc h |
0.8948±0.0304884 |
Z-Score: |
-4.3491±1.44685 |
p-Value: |
0.000440462 |
Z-Factor: |
-0.870248 |
Fitness Defect: |
7.7277 |
Bioactivity Statement: |
Active |
Experimental Conditions | | Library: | Lopac | Plate Number and Position: | 2|G5 | Drug Concentration: | 50.00 nM | OD Absorbance: | 600 nm | Robot Temperature: | 26.90 Celcius | Date: | 2005-11-16 YYYY-MM-DD | Plate CH Control (+): | 0.03855±0.00129 | Plate DMSO Control (-): | 0.64055±0.02116 | Plate Z-Factor: | 0.8634 |
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11303 |
(3S,5S)-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren -17-one |
15020 |
(1S,5S,8S,9S,10S,13S,14S,17S)-17-hydroxy-1,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahy drocyclopenta[a]phenanthren-3-one |
16067 |
(17S)-17-hydroxy-13,17-dimethyl-1,2,4,5,6,7,8,9,10,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren -3-one |
18650 |
(5R,17S)-17-hydroxy-10,13,17-trimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanth ren-3-one |
22934 |
(5S,17S)-17-hydroxy-13,17-dimethyl-1,2,4,5,6,7,8,9,10,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanth ren-3-one |
25012 |
(4S,5S,17S)-17-hydroxy-4,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]ph enanthren-3-one |
internal high similarity DBLink | Rows returned: 5 | |
active | Cluster 11774 | Additional Members: 14 | Rows returned: 5 | |
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