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Compound InformationSONAR Target prediction
Name:

Androsterone

Unique Identifier:LOPAC 00697
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C19H30O2
Molecular Weight:263.226 g/mol
X log p:-0.358  (online calculus)
Lipinksi Failures0
TPSA17.07
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:2
Rotatable Bond Count:0
Canonical Smiles:CC12CCC(O)CC1CCC1C2CCC2(C)C1CCC2=O
Class:Hormone
Selectivity:Androgen
Generic_name:AETIOCHOLANOLONE
Chemical_iupac_name:AETIOCHOLANOLONE
Drug_type:Experimental
Drugbank_id:EXPT00443
Drug_category:Alcohol Sulfotransferase inhibitor
Organisms_affected:-1

Found: 2 active | as graph: single | with analogs << Back 1 2
Species: 4932
Condition: SMI1
Replicates: 2
Raw OD Value: r im 0.4161±0.0556493
Normalized OD Score: sc h 0.6360±0.0939235
Z-Score: -10.0747±3.36632
p-Value: 0.00000000000000710878
Z-Factor: -0.382943
Fitness Defect: 32.5774
Bioactivity Statement: Active
Experimental Conditions
Library:Lopac
Plate Number and Position:2|G5
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.10 Celcius
Date:2005-11-15 YYYY-MM-DD
Plate CH Control (+):0.038875±0.00156
Plate DMSO Control (-):0.665675±0.04194
Plate Z-Factor:0.8595
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DBLink | Rows returned: 323[1] << Back 21 22 23 24 25 26 27 28 29 30  Next >> [54]
623134 17-(5,6-dimethylheptan-2-yl)-12-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydroc
yclopenta[a]phenanthren-3-one
623591 8a-(hydroxymethyl)-4,4a,6a,6b,11,11,14a-heptamethyl-2,4,5,6,6a,7,8,9,10,12,12a,13,14,14b-tetradecahydro-
1H-picen-3-one
623875 3-hydroxy-13-methyl-2,3,4,5,6,7,8,9,10,11,12,14,15,16-tetradecahydro-1H-cyclopenta[a]phenanthren-17-one
626001 10-hydroxy-2,2,4a,6a,8a,9,14a-heptamethyl-1,3,4,5,6,6b,7,8,9,10,11,12,12a,13,14,14b-hexadecahydropicene-
6a-carbaldehyde
627591 17-hydroxy-4,4,13-trimethyl-1,2,5,6,7,8,9,10,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-
one
629113 17-hydroxy-4,4,10,13-tetramethyl-2,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3
-one

internal high similarity DBLink | Rows returned: 5
LOPAC 01140 0.9474
LOPAC 01166 1.0000
NRB 03688 1.0000
SPE00100303 1.0000
SPE00310009 1.0000

active | Cluster 11774 | Additional Members: 14 | Rows returned: 5
SPE00107108 0.377049180327869
SPE00107113 0.353846153846154
SPE01503675 0.34375
SPE00100586 0.275862068965517
SPE00310009 0

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