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Compound InformationSONAR Target prediction
Name:

L-2-aminoadipic acid

Unique Identifier:LOPAC 00681
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C6H11NO4
Molecular Weight:150.069 g/mol
X log p:-2.249  (online calculus)
Lipinksi Failures0
TPSA34.14
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:5
Rotatable Bond Count:5
Canonical Smiles:NC(CCCC(O)=O)C(O)=O
Class:Glutamate
Action:Inhibitor
Selectivity:Glutamine synthetase

Found: 24 nonactive as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [24]
Species: 4932
Condition: CLN3
Replicates: 2
Raw OD Value: r im 0.7412±0.0175362
Normalized OD Score: sc h 1.0826±0.02752
Z-Score: 2.7957±0.48792
p-Value: 0.00797172
Z-Factor: -1.43836
Fitness Defect: 4.8319
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:2|B2
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.80 Celcius
Date:2005-05-08 YYYY-MM-DD
Plate CH Control (+):0.04875±0.00419
Plate DMSO Control (-):0.702625±0.04286
Plate Z-Factor:0.8237
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DBLink | Rows returned: 9<< Back 1 2
5460399 (2S)-2-aminohexanedioate
6992111 (2S)-2-azaniumylhexanedioate
6994046 (2R)-2-azaniumylhexanedioate

internal high similarity DBLink | Rows returned: 1
SPE01502128 0.9286

active | Cluster 4071 | Additional Members: 12 | Rows returned: 0
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