Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

Amiprilose hydrochloride

Unique Identifier:LOPAC 00658
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C14ClH28NO6
Molecular Weight:313.606 g/mol
X log p:-0.87  (online calculus)
Lipinksi Failures0
TPSA40.16
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:7
Rotatable Bond Count:7
Canonical Smiles:Cl.CN(C)CCCOC1C(OC2OC(C)(C)OC21)C(O)CO
Class:Immune System
Action:Modulator

Found: 24 nonactive as graph: single | with analogs [1] << Back 11 12 13 14 15 16 17 18 19 20  Next >> [24]
Species: 4932
Condition: NOP13
Replicates: 2
Raw OD Value: r im 0.8497±0.199192
Normalized OD Score: sc h 1.0074±0.0149513
Z-Score: 0.2972±0.655473
p-Value: 0.657382
Z-Factor: -4.51708
Fitness Defect: 0.4195
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:1|E8
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:0.00 Celcius
Date:2005-04-22 YYYY-MM-DD
Plate CH Control (+):0.0587±0.00658
Plate DMSO Control (-):0.73055±0.25803
Plate Z-Factor:-0.3563
png
ps
pdf

DBLink | Rows returned: 12<< Back 1 2
5702213 1-[(3R,4S,5R)-4-(3-dimethylaminopropoxy)-7,7-dimethyl-2,6,8-trioxabicyclo[3.3.0]oct-3-yl]ethane-1,2-diol
6420050 1-[(3R,4S,5S)-4-(3-dimethylaminopropoxy)-7,7-dimethyl-2,6,8-trioxabicyclo[3.3.0]oct-3-yl]ethane-1,2-diol
hydrochloride
6602490 (1S)-1-[(4S,5S)-4-(3-dimethylaminopropoxy)-7,7-dimethyl-2,6,8-trioxabicyclo[3.3.0]oct-3-yl]ethane-1,2-di
ol
6603708 (1R)-1-[(1S,3S,4S,5R)-4-(3-dimethylaminopropoxy)-7,7-dimethyl-2,6,8-trioxabicyclo[3.3.0]oct-3-yl]ethane-
1,2-diol
6604419 (1R)-1-[(1S,3R,4R,5S)-4-(3-dimethylaminopropoxy)-7,7-dimethyl-2,6,8-trioxabicyclo[3.3.0]oct-3-yl]ethane-
1,2-diol
6713980 1-[(3R,4S,5S)-4-(3-dimethylaminopropoxy)-7,7-dimethyl-2,6,8-trioxabicyclo[3.3.0]oct-3-yl]ethane-1,2-diol

internal high similarity DBLink | Rows returned: 1
SPE01503083 1.0000

active | Cluster 11451 | Additional Members: 4 | Rows returned: 1
SPE01503083 0

Service provided by the Mike Tyers Laboratory