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Compound InformationSONAR Target prediction
Name:

Apigenin

Unique Identifier:LOPAC 00653
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C15H10O5
Molecular Weight:260.158 g/mol
X log p:14.697  (online calculus)
Lipinksi Failures1
TPSA26.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:5
Rotatable Bond Count:1
Canonical Smiles:Oc1ccc(cc1)C1Oc2cc(O)cc(O)c2C(=O)C=1
Class:Cell Cycle
Action:Inhibitor

Found: 24 nonactive as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [24]
Species: 4932
Condition: KRE1
Replicates: 2
Raw OD Value: r im 0.6868±0.0183141
Normalized OD Score: sc h 1.0014±0.00786724
Z-Score: 0.0654±0.338228
p-Value: 0.811376
Z-Factor: -24.4571
Fitness Defect: 0.209
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:1|G6
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.90 Celcius
Date:2005-11-22 YYYY-MM-DD
Plate CH Control (+):0.0389±0.00106
Plate DMSO Control (-):0.6550750000000001±0.01492
Plate Z-Factor:0.9215
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DBLink | Rows returned: 1
5280443 5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one

internal high similarity DBLink | Rows returned: 252 3 4 5 Next >> 
SPE00201315 0.9041
NRB 02680 0.9041
JFD 00153 0.9051
RJC 01511 0.9254
BTB 10082 0.9265
JFD 00148 0.9296

nonactive | Cluster 1884 | Additional Members: 20 | Rows returned: 122 Next >> 
SPE01500717 0.452830188679245
SPE01500724 0.345454545454545
SPE01504115 0.294117647058823
SPE00200499 0.24
Prest49 0.24
Prest1131 0.191489361702128

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