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Compound InformationSONAR Target prediction
Name:

Apigenin

Unique Identifier:LOPAC 00653
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C15H10O5
Molecular Weight:260.158 g/mol
X log p:14.697  (online calculus)
Lipinksi Failures1
TPSA26.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:5
Rotatable Bond Count:1
Canonical Smiles:Oc1ccc(cc1)C1Oc2cc(O)cc(O)c2C(=O)C=1
Class:Cell Cycle
Action:Inhibitor

Found: 24 nonactive as graph: single | with analogs [1] << Back 11 12 13 14 15 16 17 18 19 20  Next >> [24]
Species: 4932
Condition: LGE1
Replicates: 2
Raw OD Value: r im 0.4754±0.00678822
Normalized OD Score: sc h 0.9853±0.00686359
Z-Score: -0.5063±0.250292
p-Value: 0.618164
Z-Factor: -7.34377
Fitness Defect: 0.481
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:1|G6
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.10 Celcius
Date:2005-11-29 YYYY-MM-DD
Plate CH Control (+):0.039525±0.00295
Plate DMSO Control (-):0.472025±0.00919
Plate Z-Factor:0.8920
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DBLink | Rows returned: 1
5280443 5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one

internal high similarity DBLink | Rows returned: 25<< Back 1 2 3 4 5 Next >> 
SEW 02742 0.9296
SPE01504068 0.9320
SPE00240958 0.9353
JFD 02380 0.9366
SPE01504002 0.9371
BTB 14489 0.9403

active | Cluster 1884 | Additional Members: 20 | Rows returned: 6
SPE01500724 0.345454545454545
SPE01504115 0.294117647058823
SPE00200499 0.24
SPE01505144 0.191489361702128
SPE01500709 0.191489361702128
Prest122 0.1875

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