Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

Etoposide

Unique Identifier:LOPAC 00610
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C29H32O13
Molecular Weight:560.334 g/mol
X log p:8.656  (online calculus)
Lipinksi Failures2
TPSA100.14
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:13
Rotatable Bond Count:5
Canonical Smiles:COc1cc(cc(OC)c1O)C1C2C(COC2=O)C(OC2OC3COC(C)OC3(O)CC2O)c2cc3OCOc3cc12
Class:Apoptosis
Action:Inhibitor
Selectivity:Topo II

Found: 24 nonactive as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [24]
Species: 4932
Condition: CLN3
Replicates: 2
Raw OD Value: r im 0.6861±0.0150614
Normalized OD Score: sc h 1.1159±0.025393
Z-Score: 4.1059±1.54366
p-Value: 0.00128747
Z-Factor: -0.918509
Fitness Defect: 6.6551
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:6|B11
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.90 Celcius
Date:2005-05-08 YYYY-MM-DD
Plate CH Control (+):0.04605±0.00089
Plate DMSO Control (-):0.6449499999999999±0.04711
Plate Z-Factor:0.7541
png
ps
pdf

DBLink | Rows returned: 1
6603835

internal high similarity DBLink | Rows returned: 1
SPE01500903 0.9813

active | Cluster 2906 | Additional Members: 14 | Rows returned: 0
Service provided by the Mike Tyers Laboratory