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Compound InformationSONAR Target prediction
Name:

Minocycline hydrochloride

Unique Identifier:LOPAC 00607
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C24ClH29N2O7
Molecular Weight:465.735 g/mol
X log p:4.163  (online calculus)
Lipinksi Failures0
TPSA54.45
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:9
Rotatable Bond Count:3
Canonical Smiles:Cl.CC(C)C1C2CC3Cc4c(ccc(O)c4C(=O)C3=C(O)C2(O)C(=O)C(C(N)=O)=C1O)N(C)C
Class:Cell Cycle
Action:Inhibitor

Found: 24 nonactive as graph: single | with analogs [1] << Back 21 22 23 24
Species: 4932
Condition: WHI5
Replicates: 2
Raw OD Value: r im 0.6196±0.0238295
Normalized OD Score: sc h 0.9924±0.0313248
Z-Score: -0.2853±0.974558
p-Value: 0.5081
Z-Factor: -6.03985
Fitness Defect: 0.6771
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:11|A3
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:0.00 Celcius
Date:2005-04-20 YYYY-MM-DD
Plate CH Control (+):0.046275±0.00039
Plate DMSO Control (-):0.669425±0.10050
Plate Z-Factor:0.3936
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 0

nonactive | Cluster 12393 | Additional Members: 20 | Rows returned: 161 2 3 Next >> 
LAT004C03 0.554347826086957
SPE01505684 0.452631578947368
SPE01500414 0.448275862068966
Prest626 0.448275862068966
Prest235 0.353658536585366
LAT001B08 0.353658536585366

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