Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

Minocycline hydrochloride

Unique Identifier:LOPAC 00607
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C24ClH29N2O7
Molecular Weight:465.735 g/mol
X log p:4.163  (online calculus)
Lipinksi Failures0
TPSA54.45
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:9
Rotatable Bond Count:3
Canonical Smiles:Cl.CC(C)C1C2CC3Cc4c(ccc(O)c4C(=O)C3=C(O)C2(O)C(=O)C(C(N)=O)=C1O)N(C)C
Class:Cell Cycle
Action:Inhibitor

Found: 24 nonactive as graph: single | with analogs [1] << Back 11 12 13 14 15 16 17 18 19 20  Next >> [24]
Species: 4932
Condition: SAP30
Replicates: 2
Raw OD Value: r im 0.7954±0.0113844
Normalized OD Score: sc h 0.9808±0.00100537
Z-Score: -1.6605±0.192881
p-Value: 0.0999064
Z-Factor: -1.31685
Fitness Defect: 2.3035
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:11|A3
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:26.20 Celcius
Date:2005-11-18 YYYY-MM-DD
Plate CH Control (+):0.0388±0.11468
Plate DMSO Control (-):0.793825±0.01414
Plate Z-Factor:-0.1254
png
ps
pdf

DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 0

nonactive | Cluster 12393 | Additional Members: 20 | Rows returned: 161 2 3 Next >> 
LAT004C03 0.554347826086957
SPE01505684 0.452631578947368
SPE01500414 0.448275862068966
Prest626 0.448275862068966
Prest235 0.353658536585366
LAT001B08 0.353658536585366

Service provided by the Mike Tyers Laboratory