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Compound InformationSONAR Target prediction
Name:

Mianserin hydrochloride

Unique Identifier:LOPAC 00546
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C18ClH21N2
Molecular Weight:279.659 g/mol
X log p:17.72  (online calculus)
Lipinksi Failures1
TPSA6.48
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:2
Rotatable Bond Count:0
Canonical Smiles:Cl.CN1CCN2C(C1)c1ccccc1Cc1ccccc21
Class:Serotonin
Action:Antagonist

Found: 24 nonactive as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [24]
Species: 4932
Condition: GIM3
Replicates: 4
Raw OD Value: r im 0.5060±0.0716079
Normalized OD Score: sc h 0.9735±0.00945946
Z-Score: -0.6084±0.337973
p-Value: 0.551058
Z-Factor: -5.76708
Fitness Defect: 0.5959
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:10|C5
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.70 Celcius
Date:2005-04-08 YYYY-MM-DD
Plate CH Control (+):0.0449625±0.00068
Plate DMSO Control (-):0.6567000000000002±0.13731
Plate Z-Factor:-0.1642
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DBLink | Rows returned: 5
4184
68551
154315
154412
657192

internal high similarity DBLink | Rows returned: 1
SPE02300292 1.0000

active | Cluster 12662 | Additional Members: 3 | Rows returned: 0
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