Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

Mianserin hydrochloride

Unique Identifier:LOPAC 00546
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C18ClH21N2
Molecular Weight:279.659 g/mol
X log p:17.72  (online calculus)
Lipinksi Failures1
TPSA6.48
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:2
Rotatable Bond Count:0
Canonical Smiles:Cl.CN1CCN2C(C1)c1ccccc1Cc1ccccc21
Class:Serotonin
Action:Antagonist

Found: 24 nonactive as graph: single | with analogs [1] << Back 21 22 23 24
Species: 4932
Condition: WHI5
Replicates: 2
Raw OD Value: r im 0.6239±0.030052
Normalized OD Score: sc h 0.9846±0.0208666
Z-Score: -0.5031±0.686833
p-Value: 0.654446
Z-Factor: -7.63066
Fitness Defect: 0.424
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:10|C5
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:0.00 Celcius
Date:2005-04-20 YYYY-MM-DD
Plate CH Control (+):0.045975±0.00101
Plate DMSO Control (-):0.66755±0.06920
Plate Z-Factor:0.5902
png
ps
pdf

DBLink | Rows returned: 5
4184
68551
154315
154412
657192

internal high similarity DBLink | Rows returned: 1
SPE02300292 1.0000

active | Cluster 12662 | Additional Members: 3 | Rows returned: 0
Service provided by the Mike Tyers Laboratory