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Compound Information
SONAR Target prediction
Name:
Pregnenolone sulfate sodium
Unique Identifier:
LOPAC 00530
MolClass:
Checkout models in
ver1.5
and
ver1.0
Molecular Formula:
C21H31NaO5S
Molecular Weight:
387.277 g/mol
X log p:
0.448
(online calculus)
Lipinksi Failures
0
TPSA
91.88
Hydrogen Bond Donor Count:
0
Hydrogen Bond Acceptors Count:
5
Rotatable Bond Count:
3
Canonical Smiles:
[Na+].[O-]S(=O)(=O)OC1CCC2(C)C3CCC4(C)C(CCC4C(C)=O)C3CC=C2C1
Class:
GABA
Action:
Antagonist
Selectivity:
GABA-A
Found: 24 nonactive as graph:
single
|
with analogs
[1]
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[24]
Species:
4932
Condition:
KRE1
Replicates:
2
Raw OD Value:
r
im
0.6225±0.0173948
Normalized OD Score:
sc
h
0.9637±0.00493912
Z-Score:
-1.5554±0.266655
p-Value:
0.126413
Z-Factor:
-4.58518
Fitness Defect:
2.0682
Bioactivity Statement:
Nonactive
Experimental Conditions
Library:
Lopac
Plate Number and Position:
13|A9
Drug Concentration:
50.00 nM
OD Absorbance:
600 nm
Robot Temperature:
27.90 Celcius
Date:
2005-11-22 YYYY-MM-DD
Plate CH Control (+):
0.03925±0.00175
Plate DMSO Control (-):
0.634375±0.02407
Plate Z-Factor:
0.8702
png
ps
pdf
DBLink | Rows returned: 19
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6604147
(3R,8S,9S,10S,13S,14R,17R)-17-acetyl-10,13-dimethyl-3-sulfooxy-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro
-1H-cyclopenta[a]phenanthrene
internal high similarity DBLink | Rows returned: 0
active
| Cluster 7902 | Additional Members: 9 | Rows returned: 4
SPE01505123
0.435897435897436
SPE00270029
0.405797101449275
SPE01500645
0.276923076923077
SPE01505713
0.205882352941177
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