Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

(±)-p-Chlorophenylalanine

Unique Identifier:LOPAC 00493
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C9ClH10NO2
Molecular Weight:189.555 g/mol
X log p:7.634  (online calculus)
Lipinksi Failures1
TPSA17.07
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:3
Rotatable Bond Count:3
Canonical Smiles:NC(Cc1ccc(Cl)cc1)C(O)=O
Class:Neurotransmission
Action:Inhibitor
Selectivity:Tryptophan hydroxylase

Found: 24 nonactive as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [24]
Species: 4932
Condition: ESC2
Replicates: 2
Raw OD Value: r im 0.5867±0.0386787
Normalized OD Score: sc h 1.0227±0.00657816
Z-Score: 0.6986±0.159181
p-Value: 0.487568
Z-Factor: -3.15772
Fitness Defect: 0.7183
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:4|E7
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:28.20 Celcius
Date:2005-11-25 YYYY-MM-DD
Plate CH Control (+):0.03925±0.00540
Plate DMSO Control (-):0.588475±0.03095
Plate Z-Factor:0.8641
png
ps
pdf

DBLink | Rows returned: 101 2 Next >> 
4652 2-amino-3-(4-chlorophenyl)propanoic acid
39972 [1-carboxy-2-(4-chlorophenyl)ethyl]azanium chloride
450582 2-amino-3-(4-chlorophenyl)propanoic acid
560265 2-amino-3-(4-chlorophenyl)-2-methyl-propanoic acid
667429 (2R)-2-amino-3-(4-chlorophenyl)propanoic acid
736190 (2S)-2-amino-3-(4-chlorophenyl)propanoic acid

internal high similarity DBLink | Rows returned: 1
SPE01502162 1.0000

nonactive | Cluster 1385 | Additional Members: 11 | Rows returned: 6
LOPAC 01033 0.444444444444444
SPE01500382 0.444444444444444
SPE01502162 0.384615384615385
LOPAC 00912 0
LAT003F10 0
SPE01502114 0

Service provided by the Mike Tyers Laboratory