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Compound InformationSONAR Target prediction
Name:

Acyclovir

Unique Identifier:LOPAC 00490
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C8H11N5O3
Molecular Weight:214.117 g/mol
X log p:0.77  (online calculus)
Lipinksi Failures0
TPSA54.26
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:8
Rotatable Bond Count:4
Canonical Smiles:NC1NC(=O)c2ncn(COCCO)c2N=1
Class:Immune System
Action:Inhibitor
Selectivity:Viral DNA synthesis
Generic_name:9-HYROXYETHOXYMETHYLGUANINE
Chemical_iupac_name:9-HYROXYETHOXYMETHYLGUANINE
Drug_type:Experimental
Drugbank_id:EXPT00406
Drug_category:Thymidine Kinase inhibitor
Organisms_affected:-1

Found: 24 nonactive as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [24]
Species: 4932
Condition: GIM3
Replicates: 4
Raw OD Value: r im 0.5469±0.0322943
Normalized OD Score: sc h 0.9982±0.0076558
Z-Score: -0.0630±0.163504
p-Value: 0.885208
Z-Factor: -4.2964
Fitness Defect: 0.1219
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:1|D8
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.50 Celcius
Date:2005-04-08 YYYY-MM-DD
Plate CH Control (+):0.04434999999999999±0.00279
Plate DMSO Control (-):0.6851375±0.15133
Plate Z-Factor:-0.3271
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 3
HTS 11460 0.9435
LOPAC 00932 0.9833
SPE01503603 1.0000

active | Cluster 590 | Additional Members: 7 | Rows returned: 1
SPE01503603 0

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