| Compound Information | SONAR Target prediction | | Name: | NADPH tetrasodium | | Unique Identifier: | LOPAC 00455 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | C21H26N7Na4O17P3 | | Molecular Weight: | 807.142 g/mol | | X log p: | 5.025 (online calculus) | | Lipinksi Failures | 3 | | TPSA | 288.89 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 24 | | Rotatable Bond Count: | 13 | | Canonical Smiles: | [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OC1C(O)C(COP([O-])(=O)OP([O-])(
=O)OCC2OC(C(O)C2O)N2C=CCC(=C2)C(N)=O)OC1n1cnc2c(N)ncnc12 | | Class: | Nitric Oxide | | Action: | Cofactor | | Generic_name: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUC | | Chemical_iupac_name: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDEPHOSPHATE | | Drug_type: | Experimental | | Drugbank_id: | EXPT02321 | | Drug_category: | Pteridine Reductase inhibitor | | Organisms_affected: | -1 |
| Species: |
4932 |
| Condition: |
CLN3 |
| Replicates: |
2 |
| Raw OD Value: r im |
0.6577±0.00247487 |
| Normalized OD Score: sc h |
0.9893±0.0103321 |
| Z-Score: |
-0.4016±0.420541 |
| p-Value: |
0.700752 |
| Z-Factor: |
-15.2007 |
| Fitness Defect: |
0.3556 |
| Bioactivity Statement: |
Nonactive |
| Experimental Conditions | | | Library: | Lopac | | Plate Number and Position: | 11|H9 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 600 nm | | Robot Temperature: | 27.90 Celcius | | Date: | 2005-05-08 YYYY-MM-DD | | Plate CH Control (+): | 0.048424999999999996±0.00168 | | Plate DMSO Control (-): | 0.674725±0.04792 | | Plate Z-Factor: | 0.7519 |
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| 15983949 |
1-[(2R,3R,4S,5R)-5-[[[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonatooxy-oxolan-2-yl]methox
y-oxido-phosphoryl]oxy-oxido-phosphoryl]oxymethyl]-3,4-dihydroxy-oxolan-2-yl]-4H-pyridine-3-carboxamide |
| internal high similarity DBLink | Rows returned: 0 | |
| active | Cluster 306 | Additional Members: 11 | Rows returned: 0 | |
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