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Compound InformationSONAR Target prediction
Name:

Genistein

Unique Identifier:LOPAC 00433
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C15H10O5
Molecular Weight:260.158 g/mol
X log p:14.737  (online calculus)
Lipinksi Failures1
TPSA26.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:5
Rotatable Bond Count:1
Canonical Smiles:Oc1ccc(cc1)C1=COc2cc(O)cc(O)c2C1=O
Class:Phosphorylation
Action:Inhibitor
Selectivity:Tyrosine kinase
Generic_name:5,7-DIHYDROXY-3-(4-HYDROXYPHENYL)-4H-1-B
Chemical_iupac_name:GENISTEIN
Drug_type:Experimental
Kegg_compound_id:C06563
Drugbank_id:EXPT01582
Logp:1.89
Cas_registry_number:446-72-0
Drug_category:Estrogen Receptor Beta inhibitor
Organisms_affected:-1

Found: 24 nonactive as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [24]
Species: 4932
Condition: GAS1
Replicates: 2
Raw OD Value: r im 0.6659±0.0115258
Normalized OD Score: sc h 0.9921±0.00420371
Z-Score: -0.3787±0.20185
p-Value: 0.707782
Z-Factor: -5.28989
Fitness Defect: 0.3456
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:7|D11
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.30 Celcius
Date:2005-11-17 YYYY-MM-DD
Plate CH Control (+):0.039575±0.00156
Plate DMSO Control (-):0.6731499999999999±0.01603
Plate Z-Factor:0.9256
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DBLink | Rows returned: 2
5280961 5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one
11000304 6,8-dideuterio-5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one

internal high similarity DBLink | Rows returned: 17<< Back 1 2 3
RJC 00206 0.9836
SPE00240565 0.9916
SPE10100003 0.9917
LOPAC 00426 0.9918
SPE00210296 1.0000

active | Cluster 14679 | Additional Members: 9 | Rows returned: 5
SPE01500726 0.362068965517241
SPE00210296 0.269230769230769
SPE10100004 0.245283018867924
SPE00240565 0.235294117647059
SPE10100003 0

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