Compound Information | SONAR Target prediction | Name: | Genistein | Unique Identifier: | LOPAC 00433 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | C15H10O5 | Molecular Weight: | 260.158 g/mol | X log p: | 14.737 (online calculus) | Lipinksi Failures | 1 | TPSA | 26.3 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 5 | Rotatable Bond Count: | 1 | Canonical Smiles: | Oc1ccc(cc1)C1=COc2cc(O)cc(O)c2C1=O | Class: | Phosphorylation | Action: | Inhibitor | Selectivity: | Tyrosine kinase | Generic_name: | 5,7-DIHYDROXY-3-(4-HYDROXYPHENYL)-4H-1-B | Chemical_iupac_name: | GENISTEIN | Drug_type: | Experimental | Kegg_compound_id: | C06563 | Drugbank_id: | EXPT01582 | Logp: | 1.89 | Cas_registry_number: | 446-72-0 | Drug_category: | Estrogen Receptor Beta inhibitor | Organisms_affected: | -1 |
Species: |
4932 |
Condition: |
NUM1 |
Replicates: |
2 |
Raw OD Value: r im |
0.7393±0.00523259 |
Normalized OD Score: sc h |
0.9963±0.0136619 |
Z-Score: |
-0.1866±0.817437 |
p-Value: |
0.569998 |
Z-Factor: |
-9.8633 |
Fitness Defect: |
0.5621 |
Bioactivity Statement: |
Nonactive |
Experimental Conditions | | Library: | Lopac | Plate Number and Position: | 7|D11 | Drug Concentration: | 50.00 nM | OD Absorbance: | 600 nm | Robot Temperature: | 26.90 Celcius | Date: | 2005-11-30 YYYY-MM-DD | Plate CH Control (+): | 0.038825±0.00100 | Plate DMSO Control (-): | 0.73985±0.00613 | Plate Z-Factor: | 0.9730 |
| png ps pdf |
DBLink | Rows returned: 2 | |
5280961 |
5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one |
11000304 |
6,8-dideuterio-5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one |
active | Cluster 14679 | Additional Members: 9 | Rows returned: 5 | |
|