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Compound InformationSONAR Target prediction
Name:

Forskolin

Unique Identifier:LOPAC 00432
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C22H34O7
Molecular Weight:376.231 g/mol
X log p:-0.972  (online calculus)
Lipinksi Failures0
TPSA52.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:7
Rotatable Bond Count:3
Canonical Smiles:CC(=O)OC1C(O)C2C(C)(C)CCC(O)C2(C)C2(O)C(=O)CC(C)(OC12C)C=C
Class:Cyclic Nucleotides
Action:Activator
Selectivity:Adenylate cyclase
Generic_name:FORSKOLIN
Chemical_iupac_name:FORSKOLIN
Drug_type:Experimental
Drugbank_id:EXPT01467
Drug_category:Adenylyl Cyclase inhibitor
Organisms_affected:-1

Found: 24 nonactive as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [24]
Species: 4932
Condition: GIM3
Replicates: 4
Raw OD Value: r im 0.5696±0.0687009
Normalized OD Score: sc h 1.0248±0.058253
Z-Score: 0.6858±1.42847
p-Value: 0.469036
Z-Factor: -4.01941
Fitness Defect: 0.7571
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:7|A8
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.60 Celcius
Date:2005-04-08 YYYY-MM-DD
Plate CH Control (+):0.045787499999999995±0.00080
Plate DMSO Control (-):0.7115625±0.13924
Plate Z-Factor:0.1861
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DBLink | Rows returned: 111 2 Next >> 
3413
47936
337799
396205
451120
3537287

internal high similarity DBLink | Rows returned: 1
SPE01503804 1.0000

active | Cluster 2047 | Additional Members: 3 | Rows returned: 0
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