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Compound InformationSONAR Target prediction
Name:

8-Bromo-cGMP sodium

Unique Identifier:LOPAC 00416
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:BrC10H10N5NaO7P
Molecular Weight:436.004 g/mol
X log p:-1.724  (online calculus)
Lipinksi Failures1
TPSA122.66
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:12
Rotatable Bond Count:1
Canonical Smiles:[Na+].[O-]P1(=O)OCC2OC(C(O)C2O1)n1c(Br)nc2C(=O)NC(N)=Nc12
Class:Cyclic Nucleotides
Action:Activator

Found: 24 nonactive as graph: single | with analogs [1] << Back 11 12 13 14 15 16 17 18 19 20  Next >> [24]
Species: 4932
Condition: LGE1
Replicates: 2
Raw OD Value: r im 0.4546±0.0098995
Normalized OD Score: sc h 1.0044±0.0147022
Z-Score: 0.1581±0.509044
p-Value: 0.72223
Z-Factor: -23.6854
Fitness Defect: 0.3254
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:2|E11
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.10 Celcius
Date:2005-11-29 YYYY-MM-DD
Plate CH Control (+):0.03895±0.00078
Plate DMSO Control (-):0.4612±0.00788
Plate Z-Factor:0.9459
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 0

active | Cluster 1044 | Additional Members: 3 | Rows returned: 0
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