Compound Information | SONAR Target prediction | Name: | Indatraline hydrochloride | Unique Identifier: | LOPAC 00315 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | C16Cl3H16N | Molecular Weight: | 312.536 g/mol | X log p: | 16.073 (online calculus) | Lipinksi Failures | 1 | TPSA | 0 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 1 | Rotatable Bond Count: | 2 | Canonical Smiles: | Cl.CNC1CC(c2ccc(Cl)c(Cl)c2)c2ccccc12 | Class: | Dopamine | Action: | Inhibitor | Selectivity: | Reuptake |
Species: |
4932 |
Condition: |
PAC10 |
Replicates: |
2 |
Raw OD Value: r im |
0.6458±0.0126572 |
Normalized OD Score: sc h |
0.8561±0.0169426 |
Z-Score: |
-6.5470±0.853498 |
p-Value: |
0.00000000139556 |
Z-Factor: |
0.133821 |
Fitness Defect: |
20.39 |
Bioactivity Statement: |
Active |
Experimental Conditions | | Library: | Lopac | Plate Number and Position: | 9|E5 | Drug Concentration: | 50.00 nM | OD Absorbance: | 600 nm | Robot Temperature: | 27.70 Celcius | Date: | 2005-04-15 YYYY-MM-DD | Plate CH Control (+): | 0.044675±0.00095 | Plate DMSO Control (-): | 0.6952±0.01696 | Plate Z-Factor: | 0.8979 |
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DBLink | Rows returned: 5 | |
3703 |
3-(3,4-dichlorophenyl)-N-methyl-2,3-dihydro-1H-inden-1-amine |
126280 |
(1R,3R)-3-(3,4-dichlorophenyl)-N-methyl-2,3-dihydro-1H-inden-1-amine |
2794225 |
(1S,3S)-3-(3,4-dichlorophenyl)-N-methyl-2,3-dihydro-1H-inden-1-amine |
3020938 |
3-(3,4-dichlorophenyl)-N-methyl-2,3-dihydro-1H-inden-1-amine hydrochloride |
6604886 |
(1R,3S)-3-(3,4-dichlorophenyl)-N-methyl-2,3-dihydro-1H-inden-1-amine |
internal high similarity DBLink | Rows returned: 0 | |
active | Cluster 1690 | Additional Members: 4 | Rows returned: 3 | |
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