Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

JL-18

Unique Identifier:LOPAC 00288
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C18H21N5
Molecular Weight:286.226 g/mol
X log p:12.806  (online calculus)
Lipinksi Failures1
TPSA31.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:5
Rotatable Bond Count:1
Canonical Smiles:CN1CCN(CC1)C1=Nc2cccnc2Nc2ccc(C)cc21
Class:Dopamine
Action:Antagonist
Selectivity:D4>D2

Found: 24 nonactive as graph: single | with analogs [1] << Back 21 22 23 24 Next >> [24]
Species: 4932
Condition: tep1-2nd
Replicates: 2
Raw OD Value: r im 0.8634±0.00813173
Normalized OD Score: sc h 1.0120±0.00323081
Z-Score: 0.4526±0.117339
p-Value: 0.651936
Z-Factor: -19.2769
Fitness Defect: 0.4278
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:9|A7
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:0.00 Celcius
Date:2005-07-07 YYYY-MM-DD
Plate CH Control (+):0.044475±0.00224
Plate DMSO Control (-):0.8213±0.03618
Plate Z-Factor:0.8398
png
ps
pdf

DBLink | Rows returned: 1
3802

internal high similarity DBLink | Rows returned: 0

nonactive | Cluster 6723 | Additional Members: 4 | Rows returned: 3
LOPAC 00254 0
SPE01500685 0
Prest693 0

Service provided by the Mike Tyers Laboratory