| Compound Information | SONAR Target prediction | | Name: | Clozapine | | Unique Identifier: | LOPAC 00254 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | C18ClH19N4 | | Molecular Weight: | 307.672 g/mol | | X log p: | 15.894 (online calculus) | | Lipinksi Failures | 1 | | TPSA | 18.84 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 4 | | Rotatable Bond Count: | 1 | | Canonical Smiles: | CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc21 | | Class: | Dopamine | | Action: | Antagonist | | Selectivity: | D4 > D2,D3 |
| Species: |
4932 |
| Condition: |
SAP30 |
| Replicates: |
2 |
| Raw OD Value: r im |
0.7688±0.0800445 |
| Normalized OD Score: sc h |
0.9850±0.0282266 |
| Z-Score: |
-1.2126±2.35355 |
| p-Value: |
0.327794 |
| Z-Factor: |
-23.884 |
| Fitness Defect: |
1.1154 |
| Bioactivity Statement: |
Nonactive |
| Experimental Conditions | | | Library: | Lopac | | Plate Number and Position: | 4|D7 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 600 nm | | Robot Temperature: | 26.10 Celcius | | Date: | 2005-11-18 YYYY-MM-DD | | Plate CH Control (+): | 0.040249999999999994±0.00179 | | Plate DMSO Control (-): | 0.7864±0.03817 | | Plate Z-Factor: | 0.6935 |
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| DBLink | Rows returned: 0 | |
| internal high similarity DBLink | Rows returned: 1 | |
| active | Cluster 6723 | Additional Members: 4 | Rows returned: 1 | |
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