Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

Phenamil methanesulfonate

Unique Identifier:LOPAC 00229
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C13ClH16N7O4S
Molecular Weight:385.703 g/mol
X log p:8.091  (online calculus)
Lipinksi Failures1
TPSA41.79
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:8
Rotatable Bond Count:5
Canonical Smiles:CS(O)(=O)=O.Nc1nc(N)c(nc1Cl)C(=O)NC(=N)Nc1ccccc1
Class:Na+ Channel
Action:Inhibitor
Selectivity:Amiloride sensitive

Found: 24 nonactive as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [24]
Species: 4932
Condition: GAS1
Replicates: 2
Raw OD Value: r im 0.7069±0.00572756
Normalized OD Score: sc h 0.9934±0.00401367
Z-Score: -0.3187±0.192696
p-Value: 0.752212
Z-Factor: -8.7253
Fitness Defect: 0.2847
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:13|D9
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.40 Celcius
Date:2005-11-17 YYYY-MM-DD
Plate CH Control (+):0.039650000000000005±0.19027
Plate DMSO Control (-):0.70805±0.02708
Plate Z-Factor:0.8521
png
ps
pdf

DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 0

nonactive | Cluster 4060 | Additional Members: 8 | Rows returned: 71 2 Next >> 
SPE01504215 0.462962962962963
LAT002H09 0.462962962962963
LOPAC 00857 0.454545454545455
SPE01503999 0.369565217391304
SPE01500112 0
Prest15 0

Service provided by the Mike Tyers Laboratory