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Compound InformationSONAR Target prediction
Name:

Phenamil methanesulfonate

Unique Identifier:LOPAC 00229
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C13ClH16N7O4S
Molecular Weight:385.703 g/mol
X log p:8.091  (online calculus)
Lipinksi Failures1
TPSA41.79
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:8
Rotatable Bond Count:5
Canonical Smiles:CS(O)(=O)=O.Nc1nc(N)c(nc1Cl)C(=O)NC(=N)Nc1ccccc1
Class:Na+ Channel
Action:Inhibitor
Selectivity:Amiloride sensitive

Found: 24 nonactive as graph: single | with analogs 1 2 3 4 5 6 7 8 9 10  Next >> [24]
Species: 4932
Condition: BY4741
Replicates: 8
Raw OD Value: r im 0.7505±0.0633911
Normalized OD Score: sc h 0.9979±0.0249803
Z-Score: -0.0869±0.85204
p-Value: 0.755332
Z-Factor: -10.2439
Fitness Defect: 0.2806
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:13|D9
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.80 Celcius
Date:2005-04-07 YYYY-MM-DD
Plate CH Control (+):0.04800625000000002±0.00227
Plate DMSO Control (-):0.7375000000000003±0.02694
Plate Z-Factor:0.9214
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 0

nonactive | Cluster 4060 | Additional Members: 8 | Rows returned: 7<< Back 1 2
LOPAC 00165 0

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