Compound Information | SONAR Target prediction | Name: | (±)-Methoxyverapamil hydrochloride | Unique Identifier: | LOPAC 00208 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | C28ClH41N2O5 | Molecular Weight: | 479.763 g/mol | X log p: | 12.161 (online calculus) | Lipinksi Failures | 2 | TPSA | 73.18 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 7 | Rotatable Bond Count: | 14 | Canonical Smiles: | Cl.COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2cc(OC)c(OC)c(OC)c2)cc1OC | Class: | Ca2+ Channel | Action: | Antagonist | Selectivity: | L-type |
Species: |
4932 |
Condition: |
SMI1 |
Replicates: |
2 |
Raw OD Value: r im |
0.6283±0.0169706 |
Normalized OD Score: sc h |
1.0022±0.0098696 |
Z-Score: |
0.0495±0.265611 |
p-Value: |
0.851202 |
Z-Factor: |
-8.3032 |
Fitness Defect: |
0.1611 |
Bioactivity Statement: |
Nonactive |
Experimental Conditions | | Library: | Lopac | Plate Number and Position: | 10|F9 | Drug Concentration: | 50.00 nM | OD Absorbance: | 600 nm | Robot Temperature: | 27.10 Celcius | Date: | 2005-11-15 YYYY-MM-DD | Plate CH Control (+): | 0.038925±0.02430 | Plate DMSO Control (-): | 0.667825±0.02097 | Plate Z-Factor: | 0.6217 |
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6603929 |
(2S)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-propan-2-yl-2-(3,4,5-trimethoxyphenyl)pentanenitril e |
internal high similarity DBLink | Rows returned: 3 | |
nonactive | Cluster 3209 | Additional Members: 11 | Rows returned: 4 | |
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