Compound Information | SONAR Target prediction | Name: | Benztropine mesylate | Unique Identifier: | LOPAC 00174 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | C22H29NO4S | Molecular Weight: | 374.306 g/mol | X log p: | 20.956 (online calculus) | Lipinksi Failures | 1 | TPSA | 12.47 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 2 | Rotatable Bond Count: | 4 | Canonical Smiles: | CN1C2CCC1CC(C2)OC(c1ccccc1)c1ccccc1.CS(O)(=O)=O | Class: | Cholinergic | Action: | Antagonist | Selectivity: | Muscarinic |
Species: |
4932 |
Condition: |
LGE1 |
Replicates: |
2 |
Raw OD Value: r im |
0.4648±0.0175362 |
Normalized OD Score: sc h |
0.9849±0.00185787 |
Z-Score: |
-0.5162±0.0486452 |
p-Value: |
0.605926 |
Z-Factor: |
-4.21143 |
Fitness Defect: |
0.501 |
Bioactivity Statement: |
Nonactive |
Experimental Conditions | | Library: | Lopac | Plate Number and Position: | 3|D5 | Drug Concentration: | 50.00 nM | OD Absorbance: | 600 nm | Robot Temperature: | 25.30 Celcius | Date: | 2005-11-29 YYYY-MM-DD | Plate CH Control (+): | 0.038475±0.00058 | Plate DMSO Control (-): | 0.47057499999999997±0.00752 | Plate Z-Factor: | 0.9284 |
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5771553 |
(1S,5S)-3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane; methanesulfonic acid |
internal high similarity DBLink | Rows returned: 1 | |
active | Cluster 2609 | Additional Members: 7 | Rows returned: 2 | |
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