Compound Information | SONAR Target prediction | Name: | Aminobenztropine | Unique Identifier: | LOPAC 00168 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | C21H26N2O | Molecular Weight: | 296.238 g/mol | X log p: | 18.29 (online calculus) | Lipinksi Failures | 1 | TPSA | 12.47 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 3 | Rotatable Bond Count: | 4 | Canonical Smiles: | CN1C2CCC1CC(C2)OC(c1ccccc1)c1ccccc1N | Class: | Cholinergic | Action: | Ligand | Selectivity: | Muscarinic |
Species: |
4932 |
Condition: |
CIN2 |
Replicates: |
2 |
Raw OD Value: r im |
0.8472±0.0111723 |
Normalized OD Score: sc h |
1.0043±0.00189892 |
Z-Score: |
0.3347±0.1769 |
p-Value: |
0.739784 |
Z-Factor: |
-49.6914 |
Fitness Defect: |
0.3014 |
Bioactivity Statement: |
Nonactive |
Experimental Conditions | | Library: | Lopac | Plate Number and Position: | 2|E7 | Drug Concentration: | 50.00 nM | OD Absorbance: | 600 nm | Robot Temperature: | 27.00 Celcius | Date: | 2005-12-07 YYYY-MM-DD | Plate CH Control (+): | 0.0397±0.00133 | Plate DMSO Control (-): | 0.8148249999999999±0.01441 | Plate Z-Factor: | 0.9377 |
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DBLink | Rows returned: 2 | |
2143 |
2-[(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)oxy-phenyl-methyl]aniline |
6603695 |
2-[(S)-[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]oxy-phenyl-methyl]aniline |
internal high similarity DBLink | Rows returned: 1 | |
active | Cluster 2609 | Additional Members: 7 | Rows returned: 2 | |
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