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Compound InformationSONAR Target prediction
Name:

Amiloride hydrochloride

Unique Identifier:LOPAC 00165
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C6Cl2H9N7O
Molecular Weight:257.016 g/mol
X log p:-2.85  (online calculus)
Lipinksi Failures0
TPSA41.79
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:8
Rotatable Bond Count:3
Canonical Smiles:Cl.NC(=N)NC(=O)c1nc(Cl)c(N)nc1N
Class:Na+ Channel
Action:Blocker
Selectivity:Epithelial

Found: 24 nonactive as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [24]
Species: 4932
Condition: GIM3
Replicates: 4
Raw OD Value: r im 0.5117±0.0450544
Normalized OD Score: sc h 1.0067±0.041064
Z-Score: 0.1863±0.698044
p-Value: 0.755086
Z-Factor: -4.7013
Fitness Defect: 0.2809
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:2|D2
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.50 Celcius
Date:2005-04-08 YYYY-MM-DD
Plate CH Control (+):0.045725±0.00248
Plate DMSO Control (-):0.6999875±0.18996
Plate Z-Factor:-0.6400
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 2
SPE01503999 0.9016
SPE01500112 1.0000

nonactive | Cluster 4060 | Additional Members: 8 | Rows returned: 71 2 Next >> 
SPE01504215 0.462962962962963
LAT002H09 0.462962962962963
LOPAC 00857 0.454545454545455
LOPAC 00229 0.408163265306122
SPE01503999 0.369565217391304
SPE01500112 0

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