| Compound Information | SONAR Target prediction | | Name: | Thymine | | Unique Identifier: | LAT007D05 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | C5H6N2O2 | | Molecular Weight: | 120.066 g/mol | | X log p: | 1.459 (online calculus) | | Lipinksi Failures | 0 | | TPSA | 34.14 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 4 | | Rotatable Bond Count: | 0 | | Canonical Smiles: | CC1=CNC(=O)NC1=O | | Generic_name: | THYMINE | | Chemical_iupac_name: | THYMINE | | Drug_type: | Experimental | | Kegg_compound_id: | C00178 | | Drugbank_id: | EXPT03032 | | Logp: | -0.751 | | Cas_registry_number: | 65-71-4 | | Drug_category: | Thymidine Phosphorylase inhibitor | | Organisms_affected: | -1 |
| Species: |
4932 |
| Condition: |
pdr18h |
| Replicates: |
2 |
| Raw OD Value: r im |
0.6426±0.0226981 |
| Normalized OD Score: sc h |
0.9992±0.00802498 |
| Z-Score: |
0.1254±0.231658 |
| p-Value: |
0.870894 |
| Z-Factor: |
-223.759 |
| Fitness Defect: |
0.1382 |
| Bioactivity Statement: |
Nonactive |
| Experimental Conditions | | | Library: | LATCA | | Plate Number and Position: | 7|D5 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 600 nm | | Robot Temperature: | 25.50 Celcius | | Date: | 2007-03-08 YYYY-MM-DD | | Plate CH Control (+): | 0.039825±0.00225 | | Plate DMSO Control (-): | 0.6298250000000001±0.01052 | | Plate Z-Factor: | 0.9414 |
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| DBLink | Rows returned: 6 | |
| 1135 |
5-methyl-1H-pyrimidine-2,4-dione |
| 160169 |
5-methyl-1H-pyrimidine-2,4-dione |
| 426042 |
azanide; 5-methyl-1H-pyrimidine-2,4-dione; platinum(+4) cation; dihydrate |
| 430256 |
aziridine; 5-methyl-1H-pyrimidine-2,4-dione |
| 10887937 |
5-methyl-1H-pyrimidine-2,4-dione |
| 11557282 |
5-methyl-1H-pyrimidine-2,4-dione |
| internal high similarity DBLink | Rows returned: 0 | |
| active | Cluster 5359 | Additional Members: 5 | Rows returned: 2 | |
|
