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Compound InformationSONAR Target prediction
Name:

(S)-(+)-Camptothecin

Unique Identifier:LAT003C09
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C20H16N2O4
Molecular Weight:332.225 g/mol
X log p:11.182  (online calculus)
Lipinksi Failures1
TPSA58.97
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:6
Rotatable Bond Count:1
Canonical Smiles:CCC1(O)C(=O)OCC2C(=O)N3Cc4cc5ccccc5nc4C3=CC=21

Found: 4 active | as graph: single | with analogs << Back 1 2 3 4
Species: 4932
Condition: wt18h
Replicates: 2
Raw OD Value: r im 0.5495±0.0492146
Normalized OD Score: sc h 0.7042±0.0553075
Z-Score: -8.2240±0.100457
p-Value: 2.31844e-16
Z-Factor: 0.233076
Fitness Defect: 36.0005
Bioactivity Statement: Active
Experimental Conditions
Library:LATCA
Plate Number and Position:3|C9
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:24.80 Celcius
Date:2007-02-28 YYYY-MM-DD
Plate CH Control (+):0.04±0.00167
Plate DMSO Control (-):0.80105±0.01681
Plate Z-Factor:0.9253
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DBLink | Rows returned: 71 2 Next >> 
2538
24360
32939
153546
184196
10497972

internal high similarity DBLink | Rows returned: 3
LOPAC 00814 1.0000
Prest102 1.0000
SPE01502232 1.0000

active | Cluster 1530 | Additional Members: 9 | Rows returned: 5
SPE01504123 0.178082191780822
LAT002A02 0
LOPAC 00814 0
SPE01502232 0
Prest102 0

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