Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

Dactinomycin

Unique Identifier:LAT002G11
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C64H88N10O16
Molecular Weight:1164.74 g/mol
X log p:0.0749999999999996  (online calculus)
Lipinksi Failures1
TPSA274.92
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:26
Rotatable Bond Count:10
Canonical Smiles:CC(C)C1NC(=O)C(NC(=O)c2ccc(C)c3Oc4c(C)c(=O)c(N)c(C(=O)NC5C(C)OC(=O)C(C
(C)C)N(C)C(=O)CN(C)C(=O)C6CCCC6C(=O)C(NC5=O)C(C)C)c4=Nc32)C(C)OC(=O)C(
C(C)C)N(C)C(=O)CN(C)C(=O)C2CCCC2C1=O

Found: 1 active | as graph: single | with analogs
Species: 4932
Condition: pdr18h
Replicates: 2
Raw OD Value: r im 0.4828±0.0363453
Normalized OD Score: sc h 0.7642±0.0594083
Z-Score: -6.4630±1.18357
p-Value: 0.00000000921636
Z-Factor: -0.0833726
Fitness Defect: 18.5023
Bioactivity Statement: Active
Experimental Conditions
Library:LATCA
Plate Number and Position:2|G11
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.10 Celcius
Date:2007-03-08 YYYY-MM-DD
Plate CH Control (+):0.03955±0.00248
Plate DMSO Control (-):0.647475±0.01609
Plate Z-Factor:0.8987
png
ps
pdf

DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 0

active | Cluster 1492 | Additional Members: 3 | Rows returned: 1
SPE00330001 0

Service provided by the Mike Tyers Laboratory