Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

Pyrvinium Pamoate

Unique Identifier:LAT002F04
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C49H43N3O6
Molecular Weight:726.541 g/mol
X log p:29.37  (online calculus)
Lipinksi Failures1
TPSA9.49
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:2
Rotatable Bond Count:4
Canonical Smiles:[O-]C(=O)c1cc2ccccc2c(Cc2c(O)c(cc3ccccc32)C(O)=O)c1O.CN(C)c1ccc2c(ccc(
C=Cc3cc(C)n(c3C)c3ccccc3)[n+]2C)c1

Found: 4 active | as graph: single | with analogs << Back 1 2 3 4 Next >> 
Species: 4932
Condition: pdr24h
Replicates: 2
Raw OD Value: r im 0.0745±0.00247487
Normalized OD Score: sc h 0.1033±0.000393171
Z-Score: -38.4343±0.895614
p-Value: 0
Z-Factor: 0.934165
Fitness Defect: INF
Bioactivity Statement: Toxic
Experimental Conditions
Library:LATCA
Plate Number and Position:2|F4
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.10 Celcius
Date:2007-03-08 YYYY-MM-DD
Plate CH Control (+):0.040275000000000005±0.00205
Plate DMSO Control (-):0.692975±0.01342
Plate Z-Factor:0.9255
png
ps
pdf

DBLink | Rows returned: 6
427876 4-[(3-carboxy-2-hydroxy-naphthalen-1-yl)methyl]-3-hydroxy-naphthalene-2-carboxylic acid;
2-[2-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)ethenyl]-N,N,1-trimethyl-quinolin-6-amine
5476354 4-[(3-carboxy-2-hydroxy-naphthalen-1-yl)methyl]-3-hydroxy-naphthalene-2-carboxylic acid;
2-[(E)-2-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)ethenyl]-N,N,1-trimethyl-quinolin-6-amine
5702110 4-[(3-carboxy-2-hydroxy-naphthalen-1-yl)methyl]-3-hydroxy-naphthalene-2-carboxylate;
2-[(E)-2-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)ethenyl]-N,N,1-trimethyl-quinolin-6-amine
11979707 4-[(3-carboxylato-2-hydroxy-naphthalen-1-yl)methyl]-3-hydroxy-naphthalene-2-carboxylate;
2-[2-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)ethenyl]-N,N,1-trimethyl-quinolin-6-amine
11980830 4-[(3-carboxylato-2-hydroxy-naphthalen-1-yl)methyl]-3-hydroxy-naphthalene-2-carboxylate;
2-[(E)-2-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)ethenyl]-N,N,1-trimethyl-quinolin-6-amine
11980902 4-[(3-carboxylato-2-hydroxy-naphthalen-1-yl)methyl]-3-hydroxy-naphthalene-2-carboxylate;
2-[(Z)-2-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)ethenyl]-N,N,1-trimethyl-quinolin-6-amine

internal high similarity DBLink | Rows returned: 2
Prest1291 1.0000
SPE01500521 1.0000

nonactive | Cluster 6768 | Additional Members: 2 | Rows returned: 1
SPE01500521 0

Service provided by the Mike Tyers Laboratory