Compound Information | SONAR Target prediction | Name: | Pyrvinium Pamoate | Unique Identifier: | LAT002F04 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | C49H43N3O6 | Molecular Weight: | 726.541 g/mol | X log p: | 29.37 (online calculus) | Lipinksi Failures | 1 | TPSA | 9.49 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 2 | Rotatable Bond Count: | 4 | Canonical Smiles: | [O-]C(=O)c1cc2ccccc2c(Cc2c(O)c(cc3ccccc32)C(O)=O)c1O.CN(C)c1ccc2c(ccc( C=Cc3cc(C)n(c3C)c3ccccc3)[n+]2C)c1 |
Species: |
4932 |
Condition: |
pdr22h |
Replicates: |
2 |
Raw OD Value: r im |
0.0755±0.000424264 |
Normalized OD Score: sc h |
0.1096±0.000981626 |
Z-Score: |
-35.0662±4.14864 |
p-Value: |
0 |
Z-Factor: |
0.965922 |
Fitness Defect: |
INF |
Bioactivity Statement: |
Toxic |
Experimental Conditions | | Library: | LATCA | Plate Number and Position: | 2|F4 | Drug Concentration: | 50.00 nM | OD Absorbance: | 600 nm | Robot Temperature: | 26.90 Celcius | Date: | 2007-03-08 YYYY-MM-DD | Plate CH Control (+): | 0.040625±0.00276 | Plate DMSO Control (-): | 0.6738±0.00616 | Plate Z-Factor: | 0.9618 |
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DBLink | Rows returned: 6 | |
427876 |
4-[(3-carboxy-2-hydroxy-naphthalen-1-yl)methyl]-3-hydroxy-naphthalene-2-carboxylic acid; 2-[2-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)ethenyl]-N,N,1-trimethyl-quinolin-6-amine |
5476354 |
4-[(3-carboxy-2-hydroxy-naphthalen-1-yl)methyl]-3-hydroxy-naphthalene-2-carboxylic acid; 2-[(E)-2-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)ethenyl]-N,N,1-trimethyl-quinolin-6-amine |
5702110 |
4-[(3-carboxy-2-hydroxy-naphthalen-1-yl)methyl]-3-hydroxy-naphthalene-2-carboxylate; 2-[(E)-2-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)ethenyl]-N,N,1-trimethyl-quinolin-6-amine |
11979707 |
4-[(3-carboxylato-2-hydroxy-naphthalen-1-yl)methyl]-3-hydroxy-naphthalene-2-carboxylate; 2-[2-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)ethenyl]-N,N,1-trimethyl-quinolin-6-amine |
11980830 |
4-[(3-carboxylato-2-hydroxy-naphthalen-1-yl)methyl]-3-hydroxy-naphthalene-2-carboxylate; 2-[(E)-2-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)ethenyl]-N,N,1-trimethyl-quinolin-6-amine |
11980902 |
4-[(3-carboxylato-2-hydroxy-naphthalen-1-yl)methyl]-3-hydroxy-naphthalene-2-carboxylate; 2-[(Z)-2-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)ethenyl]-N,N,1-trimethyl-quinolin-6-amine |
internal high similarity DBLink | Rows returned: 2 | |
nonactive | Cluster 6768 | Additional Members: 2 | Rows returned: 1 | |
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