| Compound Information | SONAR Target prediction | | Name: | Antimycin A | | Unique Identifier: | LAT002D02 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | C27H38N2O9 | | Molecular Weight: | 496.297 g/mol | | X log p: | 8.094 (online calculus) | | Lipinksi Failures | 3 | | TPSA | 113.04 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 11 | | Rotatable Bond Count: | 13 | | Canonical Smiles: | CCCCCC1C(OC(=O)CC(C)C)C(C)OC(=O)C(NC(=O)c2cccc(NC=O)c2O)C(C)OC1=O |
| Species: |
4932 |
| Condition: |
pdr18h |
| Replicates: |
2 |
| Raw OD Value: r im |
0.5901±0.00502046 |
| Normalized OD Score: sc h |
0.9339±0.0102458 |
| Z-Score: |
-1.7169±0.155312 |
| p-Value: |
0.0878892 |
| Z-Factor: |
-0.655126 |
| Fitness Defect: |
2.4317 |
| Bioactivity Statement: |
Nonactive |
| Experimental Conditions | | | Library: | LATCA | | Plate Number and Position: | 2|D2 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 600 nm | | Robot Temperature: | 25.10 Celcius | | Date: | 2007-03-08 YYYY-MM-DD | | Plate CH Control (+): | 0.03955±0.00248 | | Plate DMSO Control (-): | 0.647475±0.01609 | | Plate Z-Factor: | 0.8987 |
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ps
pdf |
| 10075804 |
[(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7
-yl] butanoate |
| 10076545 |
[3-[(3-formamido-2-hydroxy-benzoyl)amino]-2,6-dimethyl-8-(4-methylhexyl)-4,9-dioxo-1,5-dioxonan-7-yl]
3-methylbutanoate |
| 10076869 |
[3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl]
4-methylhexanoate |
| 10098617 |
[(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxy-benzoyl)amino]-2,6-dimethyl-8-(3-methylbutyl)-4,9-dioxo-1,5-
dioxonan-7-yl] 3-methylbutanoate |
| 10323928 |
[(2R,3S,6S,7R,8R)-8-butyl-3-[(3-formamido-2-hydroxy-benzoyl)amino]-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7
-yl] 2-methylpropanoate |
| 10347837 |
[3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl]
4-methylpentanoate |
| internal high similarity DBLink | Rows returned: 3 | |
| active | Cluster 5241 | Additional Members: 4 | Rows returned: 1 | |
|
